RECENT PUBLICATIONS

References and Links to Papers - click for more details

Not an exhaustive list - for a complete list, see here

High-Yielding Flow Synthesis of a Macrocyclic Molecular Hinge
High-Yielding Flow Synthesis of a Macrocyclic Molecular Hinge

Herein, we describe two isomeric macrocycles with clamp-like open and closed geometries, which crystallize as separate polymorphs but interconvert freely in solution. Using mechanistic information from NMR kinetic studies and at-line mass spectrometry, we developed a semicontinuous flow synthesis with maximum conversions of 85–93% and over 80% selectivity for a single isomer.

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Inducing social self-sorting in organic cages to tune the shape of the internal cavity
Inducing social self-sorting in organic cages to tune the shape of the internal cavity

A combined experimental–computational approach enabled the synthesis of low-symmetry imine cages from mixtures of tetraaldehyde building blocks. This “social self-sorting” approach was applied to obtain a family of new cages containing heteroatoms, showing that pores of varying geometries and surface chemistries may be reliably accessed.

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Production of monodisperse polyurea microcapsules using microfluidics
Production of monodisperse polyurea microcapsules using microfluidics

Methods to make microcapsules–used in a broad range of healthcare and energy applications–currently suffer from poor size control, limiting the establishment of size/property relationships. Here, we use microfluidics to produce monodisperse polyurea microcapsules (PUMC) with a limonene core.

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Furo[3,2-c]coumarin-derived Fe3+ Selective Fluorescence Sensor: Synthesis, Fluorescence Study and Ap
Furo[3,2-c]coumarin-derived Fe3+ Selective Fluorescence Sensor: Synthesis, Fluorescence Study and Ap

Furocoumarin derivatives have been synthesized from single step, high yielding chemistry. They are characterized by FTIR, 1H-NMR, and, for the first time, a comprehensive UV-Vis and fluorescence spectroscopy study has been carried out to determine if these compounds can serve as useful sensors.

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Computationally-guided synthetic control over pore size in isostructural porous organic cages
Computationally-guided synthetic control over pore size in isostructural porous organic cages

Here, we narrow the pore size of a cage molecule, CC3, in a systematic way by introducing methyl groups into the cage windows. Computational crystal structure prediction was used to anticipate the packing preferences of two homochiral methylated cages, CC14-R and CC15-R, and to assess the structure–energy landscape of a CC15-R/CC3-S cocrystal, designed such that both component cages could be directed to pack with a 3-D, interconnected pore structure.

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Reticular synthesis of porous molecular 1D nanotubes and 3D networks
Reticular synthesis of porous molecular 1D nanotubes and 3D networks

Here we apply a chiral recognition strategy to a new family of tubular covalent cages to create both 1D porous nanotubes and 3D diamondoid pillared porous networks. These results are a blueprint for applying the ‘node and strut’ principles of reticular synthesis to molecular crystals.

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Dynamic flow synthesis of porous organic cages
Dynamic flow synthesis of porous organic cages

The dynamic covalent synthesis of two imine-based porous organic cages was successfully transferred from batch to continuous flow. The same flow reactor was then used to scramble the constituents of these two cages in differing ratios to form cage mixtures. Preparative HPLC purification of one of these mixtures allowed rapid access to a desymmetrised cage molecule.

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White Light Emission from a Simple Mixture of Fluorescent Organic Compounds
White Light Emission from a Simple Mixture of Fluorescent Organic Compounds

Three fluorescent organic compounds—furocoumarin (FC), dansyl aniline (DA), and 7-hydroxycoumarin3-carboxylic acid (CC)—are mixed to produce almost pure white light emission (WLE). This novel mixture is immobilised in silica aerogel and applied as a coating to a UV LED to demonstrate its applicability as a low-cost, organic coating for WLE via simultaneous emission.

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Controlling the Two-Dimensional Self-Assembly of Functionalized Porphyrins via Adenine–Thymine Quart
Controlling the Two-Dimensional Self-Assembly of Functionalized Porphyrins via Adenine–Thymine Quart

In this work, the formation of nucleobase quartets consisting of adenine and thymine groups was used to control the 2D self-assembly of porphyrins.

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A solution-processable dissymmetric porous organic cage
A solution-processable dissymmetric porous organic cage

Two dissymmetric racemic analogues of the chiral porous organic cage, CC3, were isolated and unambiguously characterised as a racemate pair of the R,R,R,S,S,S and S,S,S,R,R,R-diastereomers (CC3-RS and CC3-SR). CC3-RS/CC3-SR equals the highest porosity measured for CC3 but is an order of magnitude more soluble, making it an excellent candidate for incorporation into a membrane for separation applications.

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Ultra-Fast Molecular Rotors within Porous Organic Cages
Ultra-Fast Molecular Rotors within Porous Organic Cages

Using variable temperature 2H static NMR spectra and 13C spin-lattice relaxation times (T1), we show that two different porous organic cages with tubular architectures are ultra-fast molecular rotors.

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Function-led design of new porous materials
Function-led design of new porous materials

From kitchen sieves and strainers to coffee filters, porous materials have a wide range of uses. On an industrial scale, they are used as sorbents, filters, membranes, and catalysts. Slater and Cooper review how each application will limit the materials that can be used, and also the size and connectivity of the pores required. They go on to compare and contrast a growing range of porous materials that are finding increasing use in academic and industrial applications.

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